Drug Standards
Apexbio Technology LLC Tiamulin fumarate 55297-96-6 250mg
Tiamulin fumarate is a semi-synthetic antibiotic belonging to the pleuromutilin class specifically inhibiting bacterial protein synthesis Its primary antibacterial activity targets Gram-positive bacteria certain Gram-negative bacteria and mycoplasmas by binding to the bacterial 50S ribosomal subunit thereby blocking peptide chain elongation Laboratory studies commonly utilize Tiamulin fumarate for investigating bacterial susceptibility mechanisms antibiotic resistance profiles and antimicrobial efficacy in veterinary pathogens It is applied predominantly in veterinary research settings involving swine mycoplasmal pneumonia swine dysentery and chronic respiratory infections in poultry In vitro assays demonstrate antibacterial activity with reported minimum inhibitory concentration (MIC) values often in the low micromolar range and inhibitory concentrations (IC50) varying depending on bacterial strain and experimental conditions
Apexbio Technology LLC Metoprolol Tartrate 56392-17-7 10mM (in 1mL DMSO)
Metoprolol Tartrate (CAS 56392-17-7) is a selective 1-adrenergic receptor antagonist employed primarily for cardiovascular research purposes By specifically inhibiting 1-adrenergic receptors located predominantly in cardiac tissue it reduces sympathetic influences on heart rate and myocardial contractility Clinical research has indicated that genetic polymorphisms in 1-adrenergic receptors significantly affect individual hypertensive responses to treatment with metoprolol Due to its targeted mode of action and known genetic modulatory effects it is widely utilized in hypertension and cardiovascular pharmacogenomics studies
Apexbio Technology LLC Cefpodoxime Proxetil 87239-81-4 10mM (in 1mL DMSO)
Cefpodoxime Proxetil is an oral prodrug belonging to the third-generation cephalosporin antibiotics After absorption it undergoes enzymatic hydrolysis in vivo converting to the active metabolite cefpodoxime Cefpodoxime exerts antibacterial activity by binding bacterial penicillin-binding proteins (PBPs) and inhibiting peptidoglycan synthesis thus preventing proper cell wall formation and ultimately leading to bacterial growth inhibition Cefpodoxime Proxetil is routinely employed in biomedical research studies to evaluate its antibacterial spectrum pharmacokinetics bioavailability and bacterial resistance mechanisms Additionally researchers utilize this compound for investigating antibacterial potential via in vitro and in vivo experiments with typical IC50 values varying based on bacterial strains and experimental conditions
Medchemexpress LLC Econazole nitrate | 24169-02-6 | MFCD00058160 | 98.0% | 1 G
Econazole nitrate is an imidazole class antifungal medication that also possesses antibacterial activity. It is clinically used as a topical cream to treat various dermatological infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. Research indicates its efficacy against vaginal candidiasis and good tolerability in toxicity and teratogenicity studies.
- Imidazole class antifungal
- Possesses antibacterial activity
- Treats various skin infections
- Effective against athlete's foot, tinea, and ringworm
- Well-tolerated in studies
Medchemexpress LLC Econazole nitrate | 24169-02-6 | 98.0% | 25 G
Econazole nitrate is an imidazole class antifungal medication that also exhibits antibacterial activity. It is commonly used as a cream to treat various skin infections and has shown effectiveness in curing vaginal candidiasis via oral administration, with studies indicating it is generally well-tolerated.
- Imidazole class antifungal medication
- Exhibits antibacterial activity
- Treats skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch
- Cures vaginal candidiasis
- Generally well tolerated
Medchemexpress LLC Fenoldopam (mesylate) | 67227-57-0 | 99.9% | 50 MG
Fenoldopam (mesylate) | 67227-57-0 | 99.9% | 50 MG
Medchemexpress LLC Alverine citrate | 5560-59-8 | 99.49% | 1 G
Alverine citrate is a 5-HT1A receptor antagonist, with an IC50 of 101 nM. It is a drug used for functional gastrointestinal disorders, acting directly on the muscle in the gut to cause relaxation. In-vitro binding studies indicate that Alverine citrate has a high affinity for 5-HT1A receptors and a weak affinity for 5-HT3 and 5-HT4 subtypes. Alverine may increase Ca influx during action potentials by inhibiting the inactivation of L-type Ca channels, and may also suppress evoked activity by inhibiting the sensitivity of contractile proteins to Ca2+.
- 5-HT1A receptor antagonist
- Used for functional gastrointestinal disorders
- Acts directly on gut muscle, causing relaxation
- High affinity for 5-HT1A receptors
- Weak affinity for 5-HT3 and 5-HT4 subtypes
- Available as a solid and in solution (in DMSO)
Medchemexpress LLC Octyl gallate | 1034-01-1 | 282.33 | 5 G
Octyl gallate (Progallin O) is widely used as a food additive, possessing antimicrobial and antioxidant activity. It also exhibits selective and sensitive fluorescent properties. Furthermore, Octyl gallate has demonstrated a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV), and poliovirus.
- Widely used as a food additive
- Possesses antimicrobial and antioxidant activity
- Exhibits selective and sensitive fluorescent properties
- Demonstrates a marked antiviral effect against HSV-1, vesicular stomatitis virus (VSV), and poliovirus
Medchemexpress LLC Enalaprilat (dihydrate) | 84680-54-6 | 99.6% | 1 ML
Enalaprilat dihydrate (MK-422), the active metabolite of the oral proagent Enalapril, is a potent, competitive, and long-acting angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 1.94 nM. This product is intended for research on hypertension.
- Potent and long-acting ACE inhibitor
- Attenuates IGF-I induced neonatal rat cardiac fibroblast growth in vitro
- Shows significant intraocular pressure (IOP)-lowering effect in rabbits in vivo
Sigma Aldrich Fine Chemicals Biosciences Sodium fluoride United Sta1G
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Sigma Aldrich Fine Chemicals Biosciences Milbemycin oxime United States Pharmacopeia (USP) Reference Standard | 129496-10-2 | 200MG
Milbemycin oxime United States Pharmacopeia (USP) Reference Standard | 129496-10-2 | 200MG